Season 2: Episode 19: Fifteen Minutes of Shame
Meg is sick of being embarrassed by her family, so she ambushes them on a talk show. A network executive is intrigued by their story, and gets Peter to sign a deal to make the Griffins' daily lives into a reality series for TV. Meg can't stand it, and quits the family, living with the neighbors, while her role is re-cast with a perky blonde. When the cameras start just following the blonde around, the rest of the family realizes how silly it all is and they also quit. The entire family is re-cast with Tom Arnold and Fran Drescher playing Peter and Lois, and the real Griffins re-unite with Meg and live in a hotel.